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Efficacy and safety of vericiguat in patients with heart failure with reduced ejection fraction treated with sacubitril/valsartan: insights from the VICTORIA trial
European Journal of Heart Failure ( IF 16.9 ) Pub Date : 2022-07-05 , DOI: 10.1002/ejhf.2608
Michele Senni 1 , Wendimagegn G Alemayehu 2 , David Sim 3 , Frank Edelmann 4 , Javed Butler 5 , Justin Ezekowitz 2 , Adrian F Hernandez 6 , Carolyn S P Lam 3 , Christopher M O'Connor 7 , Burkert Pieske 4 , Piotr Ponikowski 8 , Lothar Roessig 9 , Adriaan A Voors 10 , Cynthia M Westerhout 2 , Ciaran McMullan 11 , Paul W Armstrong 2 ,
Affiliation  

We assessed a subset of the 5040 patients in VICTORIA receiving sacubitril/valsartan, either at randomization (n = 731) or post-randomization drop-in use (n = 425), to evaluate the relationship between the efficacy and safety of combination therapy with vericiguat.

中文翻译:

Vericiguat 对用沙库巴曲/缬沙坦治疗射血分数降低的心力衰竭患者的疗效和安全性:来自 VICTORIA 试验的见解

我们评估了 VICTORIA 接受沙库巴曲/缬沙坦治疗的 5040 名患者的一个子集,无论是在随机分组(n  = 731)还是在随机分组后直接使用(n  = 425),以评估联合治疗的有效性和安全性之间的关系vericiguat。
更新日期:2022-07-05
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