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Clinical, microbiological, and immunological effects of 3- or 7-day systemic antibiotics adjunctive to subgingival instrumentation in patients with aggressive (Stage III/IV Grade C) periodontitis: A randomized placebo-controlled clinical trial
Journal of Clinical Periodontology ( IF 5.8 ) Pub Date : 2022-07-04 , DOI: 10.1111/jcpe.13676
Raluca Cosgarea 1, 2, 3 , Søren Jepsen 1 , Christian Heumann 4 , Ionela Batori-Andronescu 5, 6 , Alexandra Rosu 3, 5 , Raluca Bora 3, 5 , Nicole B Arweiler 2 , Sigrun Eick 7 , Anton Sculean 7
Affiliation  

To evaluate the clinical non-inferiority of a 3-day protocol of systemic antibiotics adjunctive to subgingival instrumentation (SI) compared with a 7-day-protocol in patients with Stage III/IV Grade C periodontitis.

中文翻译:

侵袭性(III/IV 级 C 级)牙周炎患者 3 天或 7 天全身性抗生素联合龈下器械治疗的临床、微生物学和免疫学效果:一项随机安慰剂对照临床试验

评估在 III/IV 期 C 级牙周炎患者中,与 7 天方案相比,3 天方案的全身性抗生素辅助龈下器械 (SI) 的临床非劣效性。
更新日期:2022-07-04
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