Clinical, microbiological, and immunological effects of 3- or 7-day systemic antibiotics adjunctive to subgingival instrumentation in patients with aggressive (Stage III/IV Grade C) periodontitis: A randomized placebo-controlled clinical trial,Journal of Clinical Periodontology

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Clinical, microbiological, and immunological effects of 3- or 7-day systemic antibiotics adjunctive to subgingival instrumentation in patients with aggressive (Stage III/IV Grade C) periodontitis: A randomized placebo-controlled clinical trial
Journal of Clinical Periodontology ( IF 5.8 ) Pub Date : 2022-07-04 , DOI: 10.1111/jcpe.13676
Raluca Cosgarea _{1,

2,

3} , Søren Jepsen ₁ , Christian Heumann ₄ , Ionela Batori-Andronescu _{5,

6} , Alexandra Rosu _{3,

5} , Raluca Bora _{3,

5} , Nicole B Arweiler ₂ , Sigrun Eick ₇ , Anton Sculean ₇

Affiliation

To evaluate the clinical non-inferiority of a 3-day protocol of systemic antibiotics adjunctive to subgingival instrumentation (SI) compared with a 7-day-protocol in patients with Stage III/IV Grade C periodontitis.

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