Study question What is the experience of parents and their offspring when they discover they were victims of insemination fraud, i.e. a voluntary substitution of sperm samples? Summary answer Participants reported experiencing shock, sideration and disbelief, feelings of being betrayed by the medical institution, and concerns about the repercussions on family bonds. What is known already Despite growing concerns about third-party assisted human reproduction, several loopholes remain in the legislation governing sperm donation. For example, the lack of consistency across clinics in donation tracking and record-keeping procedures has led to cases of accidental or voluntary substitution of sperm donations. Such substitutions imply that the sperm of the donor selected by the parents or that of the father of the child is not the sperm used for conception. With the advent of DNA kits, more and more cases of substitution are being uncovered. However, this phenomenon has not received the scientific attention it deserves. Study design, size, duration This is an exploratory study using a qualitative methodology. Data collection was conducted in Canada in the winter of 2019 and spring of 2021 using a purposive sampling method. Participants/materials, setting, methods In total, 13 people made up our sample: seven parents (two fathers and five mothers) and six donor-conceived people conceived (four teenagers, aged between 13 and 16 years and two adults aged 38 and 39 years). Donor conception was used in the context of male infertility (N = 1), vasectomy (N = 3), sperm freezing after cancer (N = 1), and celibacy (N = 1). The data was collected using semi-structured individual interviews. Main results and the role of chance A thematic analysis shows that the experience varies according to one’s position in the insemination process (whether one uses it or is the product of it), to the nature of the substitution and to the suspicions one has (or not) prior to the discovery. However, all the participants described the announcement of the substitution as a shock that strongly undermines trust in the assisted reproduction industry. In cases where the father’s sperm was substituted, this leads to having to renounce biological paternity and the ideal of a child born to both parents. In cases where the chosen donor was substituted, this forces the parents and their offspring to give up (temporarily or permanently) the possibility of tracing the man who conceived the child and/or the donor siblings. The substitution generates then for the parents a feeling of worry about the medical and psychological repercussions for their child and, for the children, a feeling of incomplete identity. On the other hand, in cases where the doctor’s sperm was substituted for that of an unknown donor, the persons conceived by donation seemed to have a better reaction because it provided them with answers as to their origins. Limitations, reasons for caution Despite the innovative nature of the study, the size of the sample and the variability of the experiences do not allow for definitive conclusions to be drawn about this phenomenon and limit the understanding that can be gained from it to this particular fraud, emanating from the same doctor. Wider implications of the findings With the democratization of DNA testing, this type of phenomenon could become more widespread. It is therefore important to document it to better understand its consequences on the disintegration of the filial or family bond, the possibility of redefining the biological family, and the redefinition of the original parental project. Trial registration number N/A

中文翻译：

---

P-768 家庭受精欺诈的经历：定性研究

研究问题 当父母和他们的后代发现自己是受精欺诈（即自愿替换精子样本）的受害者时，他们的经历是什么？总结性回答 参与者报告说经历了震惊、偏见和怀疑、被医疗机构背叛的感觉以及对家庭纽带影响的担忧。已知情况 尽管对第三方辅助人类生殖的担忧日益增加，但有关精子捐赠的立法中仍然存在一些漏洞。例如，各个诊所在捐赠跟踪和记录保存程序方面缺乏一致性，导致了意外或自愿替换精子捐赠的案例。这种替换意味着父母选择的供体或孩子父亲的精子不是用于受孕的精子。随着 DNA 试剂盒的出现，越来越多的替代案例被发现。然而，这一现象并未得到应有的科学关注。研究设计、规模、持续时间 这是一项使用定性方法的探索性研究。数据收集于 2019 年冬季和 2021 年春季在加拿大使用有目的的抽样方法进行。参与者/材料、环境、方法 我们的样本共有 13 人：7 名父母（2 名父亲和 5 名母亲）和 6 名受孕者（4 名青少年，年龄在 13 至 16 岁之间，两名成年人，年龄在 38 至 39 岁之间）年）。供体受孕用于男性不育症（N = 1），输精管结扎术（N = 3）、癌症后精子冷冻（N = 1）和独身（N = 1）。数据是使用半结构化的个人访谈收集的。主要结果和机会的作用 主题分析表明，经验会根据一个人在授精过程中的位置（无论是使用它还是它的产物）、替代的性质和一个人的怀疑（或不是）在发现之前。然而，所有参与者都将替代的宣布描述为一种冲击，极大地破坏了对辅助生殖行业的信任。在父亲的精子被替换的情况下，这导致不得不放弃亲子关系和父母双方所生孩子的理想。在选定的捐赠者被替换的情况下，这迫使父母及其后代（暂时或永久）放弃追踪怀上孩子的男子和/或供体兄弟姐妹的可能性。这种替代会给父母带来一种担心他们的孩子的医疗和心理影响的感觉，而对于孩子来说，一种不完整的身份感。另一方面，在医生的精子被未知捐赠者的精子替代的情况下，通过捐赠受孕的人似乎有更好的反应，因为它为他们提供了关于其来源的答案。局限性，谨慎的理由 尽管这项研究具有创新性，样本的大小和经验的可变性不允许对这种现象得出明确的结论，并且限制了可以从中获得的对这种特定欺诈的理解，这种欺诈来自同一位医生。研究结果的更广泛影响随着 DNA 测试的民主化，这种现象可能会变得更加普遍。因此，重要的是记录它以更好地了解其对孝道或家庭纽带解体的后果、重新定义生物家庭的可能性以及重新定义原始父母项目的可能性。试用注册号 N/A 因此，重要的是记录它以更好地了解其对孝道或家庭纽带解体的后果、重新定义生物家庭的可能性以及重新定义原始父母项目的可能性。试用注册号 N/A 因此，重要的是记录它以更好地了解其对孝道或家庭纽带解体的后果、重新定义生物家庭的可能性以及重新定义原始父母项目的可能性。试用注册号 N/A