Progression of echocardiographic parameters and prognosis in transthyretin cardiac amyloidosis,European Journal of Heart Failure

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Progression of echocardiographic parameters and prognosis in transthyretin cardiac amyloidosis
European Journal of Heart Failure ( IF 16.9 ) Pub Date : 2022-07-02 , DOI: 10.1002/ejhf.2606
Liza Chacko ₁ , Nina Karia ₁ , Lucia Venneri ₁ , Francesco Bandera _{2,

3} , Beatrice Dal Passo ₁ , Lodovico Buonamici ₁ , Jonathan Lazari ₁ , Adam Ioannou ₁ , Aldostefano Porcari _{1,

4} , Rishi Patel ₁ , Yousuf Razvi ₁ , James Brown ₁ , Daniel Knight ₁ , Ana Martinez-Naharro ₁ , Carol Whelan ₁ , Candida C Quarta ₁ , Charlotte Manisty ₅ , James Moon ₅ , Dorota Rowczenio ₁ , Janet A Gilbertson ₁ , Helen Lachmann ₁ , Ashutosh Wechelakar ₁ , Aviva Petrie ₆ , William E Moody ₇ , Richard P Steeds ₇ , Luciano Potena ₈ , Mattia Riefolo ₉ , Ornella Leone ₉ , Claudio Rapezzi _{10,

11} , Philip N Hawkins ₁ , Julian D Gillmore ₁ , Marianna Fontana ₁

Affiliation

National Amyloidosis Centre, Division of Medicine, University College London, Royal Free Campus, London, UK.
Heart Failure Unit, Cardiology University Department, IRCCS Policlinico San Donato, Milan, Italy.
Department for Biomedical Sciences for Health, University of Milano, Milan, Italy.
Center for Diagnosis and Treatment of Cardiomyopathies, Cardiovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI), University of Trieste, Trieste, Italy.
Barts Heart Centre, The Cardiovascular Magnetic Resonance Imaging Unit, and the Inherited Cardiovascular Diseases Unit, St Bartholomew's Hospital, London, UK.
Eastman Dental Institute, University College London, London, UK.
Department of Cardiology, Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust and University of Birmingham, Birmingham, UK.
Division of Cardiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Division of Pathology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Cardiologic Center, University of Ferrara, Ferrara, Italy.
Maria Cecilia Hospital, GVM Care & Research, Cotignola, Italy.

Transthyretin amyloid cardiomyopathy (ATTR-CM) is an increasingly diagnosed disease. Echocardiography is widely utilized, but studies to confirm the value of echocardiography for tracking changes over time are not available. We sought to describe (i) changes in multiple echocardiographic parameters; (ii) differences in rate of progression of three predominant genotypes; and (iii) the ability of changes in echocardiographic parameters to predict prognosis.

中文翻译：

转甲状腺素蛋白心肌淀粉样变性超声心动图参数的进展和预后

转甲状腺素蛋白淀粉样变性心肌病 (ATTR-CM) 是一种诊断率越来越高的疾病。超声心动图应用广泛，但尚无研究证实超声心动图跟踪随时间变化的价值。我们试图描述 (i) 多个超声心动图参数的变化；(ii) 三种主要基因型的进展速度差异；(iii) 超声心动图参数变化预测预后的能力。

更新日期：2022-07-02

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