The Coronavirus Disease 2019 (COVID-19) pandemic has substantially impacted solid organ transplantation, including temporary inactivation of waitlist candidates with COVID-19 infection. We report two cases of liver transplantation (LT) in individuals with asymptomatic COVID-19 infection. The first patient is a 68-year-old female with decompensated cirrhosis complicated by worsening frailty and sarcopenia. The second patient is a 22-year-old female with acute liver failure likely secondary to drug/toxin exposure. Both patients were treated with COVID-19-directed therapies and neither patient developed symptomatic disease. These cases demonstrate that LT can be safely performed in select patients with asymptomatic COVID-19 infection at the time of transplant.

中文翻译：

---

活动性 SARS-CoV-2 感染患者肝移植成功

2019 年冠状病毒病 (COVID-19) 大流行对实体器官移植产生了重大影响，包括感染 COVID-19 的候补名单候选人的暂时失活。我们报告了两例无症状 COVID-19 感染者的肝移植 (LT) 病例。第一位患者是一名 68 岁的女性，患有失代偿性肝硬化并发虚弱和肌肉减少症。第二名患者是一名 22 岁的女性，患有可能继发于药物/毒素暴露的急性肝功能衰竭。两名患者均接受了针对 COVID-19 的治疗，均未出现症状性疾病。这些病例表明，可以在移植时对无症状 COVID-19 感染的特定患者安全地进行 LT。