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Perspectives From Advancing National Institutes of Health Research to Inform and Improve the Health of Women: A Conference Summary.
Obstetrics and Gynecology ( IF 5.7 ) Pub Date : 2022-06-07 , DOI: 10.1097/aog.0000000000004821
Sarah M Temkin 1 , Samia Noursi , Judith G Regensteiner , Pamela Stratton , Janine A Clayton
Affiliation  

The health of women remains understudied. In response to a request from Congress, the Office of Research on Women's Health of the National Institutes of Health (NIH) evaluated research on the health of women currently underway related to 1) rising rates of maternal morbidity and mortality, 2) rising rates of chronic debilitating conditions in women, and 3) stagnant cervical cancer survival rates. Input on the three priority areas was obtained from experts in women's health, members of the public, and federal stakeholders. The NIH research portfolios on these three topics were reviewed. On October 20, 2021, a conference on advancing NIH research on women's health was held to present, discuss, and delineate gaps and opportunities in the current portfolio. Across the life course, significant gaps in evidence regarding conditions, disorders, and diseases that occur in women were illustrated. Fundamental basic and translational knowledge gaps in many female-specific conditions and diseases with sex-specific presentations, symptoms, or responses to treatments have hampered the generation of robust scientific data needed to provide high-quality, evidence-based care to women. Key opportunities identified to improve the health of women include enhanced implementation of existing best practices and interventions to reduce disparities. Undertaking intentional clinical research on the health of women will produce significant returns on investment and has the potential to greatly improve human health.

中文翻译:


推进国家卫生研究院告知和改善妇女健康的观点:会议摘要。



妇女的健康状况仍未得到充分研究。应国会的要求,美国国立卫生研究院 (NIH) 妇女健康研究办公室评估了目前正在进行的有关妇女健康的研究,涉及 1) 孕产妇发病率和死亡率上升,2) 孕产妇发病率上升女性慢性衰弱状况,3) 宫颈癌存活率停滞不前。妇女健康专家、公众和联邦利益相关者就这三个优先领域提出了意见。 NIH 对这三个主题的研究组合进行了审查。 2021 年 10 月 20 日,举行了一次关于推进 NIH 女性健康研究的会议,介绍、讨论和描绘当前投资组合中的差距和机遇。在整个生命过程中,关于女性发生的状况、紊乱和疾病的证据存在显着差距。许多具有性别特异性表现、症状或治疗反应的女性特有病症和疾病的基本知识和转化知识差距阻碍了向女性提供高质量、循证护理所需的可靠科学数据的生成。已确定的改善妇女健康的关键机会包括加强现有最佳做法和干预措施的实施,以减少差距。对女性健康进行有意识的临床研究将产生显着的投资回报,并有可能极大地改善人类健康。
更新日期:2022-06-07
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