Frontiers in Veterinary Science ( IF 2.6 ) Pub Date : 2022-06-30 , DOI: 10.3389/fvets.2022.945381 Hu Xu 1 , Lirun Xiang 2 , Yan-Dong Tang 2 , Chao Li 2 , Jing Zhao 2 , Bangjun Gong 2 , Qi Sun 2 , Chaoliang Leng 3 , Jinmei Peng 2 , Qian Wang 2 , Guohui Zhou 2 , Tongqing An 2 , Xuehui Cai 2 , Zhi-Jun Tian 2 , Hongliang Zhang 2 , Mingxin Song 1
In the last decade, the emergence of QYYZ-like porcine reproductive and respiratory syndrome virus (PRRSV) has attracted increasing attention due to the high incidence of PRRSV mutation and recombination. However, the endemic status and genomic characteristics of the QYYZ-like strains are unclear. From 2018 to October 2021, 24 QYYZ-like PRRSV isolates were obtained from 787 PRRSV-positive clinical samples. Only one QYYZ-like positive sample was from a northern province, and the rest were from central and southern provinces. We selected 9 samples for whole-genome sequencing, revealing genome lengths of 15,008–15,316 nt. We retrieved all the available whole-genome sequences of QYYZ-like PRRSVs isolated in China from 2010 to 2021 (