There is considerable concern regarding antibiotic resistance in the water environment due to antibiotic residues from anthropogenic origins. The low antibiotic concentration in the water environment may promote the selection of antibiotic resistance. However, it is unclear how environmental factors affect resistance selection. We investigated the proliferation of quinolone-susceptible faecal bacteria (E. coli) exposed to low norfloxacin concentration (ng/L) at variable temperatures, exposure times, and carbon concentrations, simulating the conditions of the water environment. The induction of antibiotic resistance in thirteen E. coli isolates was more likely to occur at 37 °C. However, resistance also occurred at temperatures as low as 25 °C, provided a longer exposure time of 5 days. These results suggest that antibiotic resistance is more likely to be induced in regions where temperatures may reach 25–37 °C, such as tropical regions.

由于人为来源的抗生素残留，人们对水环境中的抗生素耐药性有相当大的关注。水环境中抗生素浓度低可能会促进抗生素耐药性的选择。然而，尚不清楚环境因素如何影响抗性选择。我们研究了在不同温度、暴露时间和碳浓度下暴露于低浓度诺氟沙星 (ng/L) 的喹诺酮类敏感粪便细菌 (大肠杆菌) 的增殖，模拟水环境条件。在 13 种大肠杆菌中诱导抗生素耐药性在 37 °C 时更有可能出现分离株。然而，在 5 天的较长暴露时间下，在低至 25 °C 的温度下也会出现阻力。这些结果表明，在温度可能达到 25-37°C 的地区，例如热带地区，更有可能诱发抗生素耐药性。