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Piezo1 senses pressure overload and initiates cardiac hypertrophy
Nature Reviews Cardiology ( IF 41.7 ) Pub Date : 2022-06-29 , DOI: 10.1038/s41569-022-00746-1 Gregory B Lim 1
Nature Reviews Cardiology ( IF 41.7 ) Pub Date : 2022-06-29 , DOI: 10.1038/s41569-022-00746-1 Gregory B Lim 1
Affiliation
The stretch-activated, calcium-permeable Piezo1 channel is the mechanosensor that transduces cardiomyocyte stretch into the biochemical signalling pathway that leads to cardiac hypertrophy in mice.
中文翻译:
Piezo1 感知压力过载并引发心脏肥大
拉伸激活的钙渗透性 Piezo1 通道是一种机械传感器,可将心肌细胞拉伸转导到导致小鼠心脏肥大的生化信号通路中。
更新日期:2022-06-29
中文翻译:
Piezo1 感知压力过载并引发心脏肥大
拉伸激活的钙渗透性 Piezo1 通道是一种机械传感器,可将心肌细胞拉伸转导到导致小鼠心脏肥大的生化信号通路中。