The biological diversity on planet earth is declining day by day, due to different factors such as excessive applications of pesticides. The utilization of chemical pesticides affected environment as well as microorganisms. The awareness among the peoples towards the hazards by the residual toxicity of chemical pesticides should be developed for agro-environmental sustainability. Entomopathogenic nematodes (EPNs) are the bacto-helminth parasites which show classical mutualism with the genera Xenorhabdus and Photorhabdus. The nematodes along with its endosymbiotic bacteria have a biocontrol potential which could be used to reduce chemical pesticides. Applications of bioagents have been reported and resulted in considerable reduction in pathogens. Furthermore, these bioagents are biodegradable, eco-friendly and easy to apply for protection of crops against diverse pathogenic organism. The nematode-bacterium complexes are effective against huge range of bacteria, fungi, nematodes and insects that are harmful to the crops. Along with biocontrol potential, the endosymbionts produce diverse secondary metabolic compounds, exoenzymes and toxic compounds that show antibiotic, antimycotic, nematicidal, miticidal and anticancerous properties. The present review deals with the diversity of endosymbiotic microbes from EPNs and their role in biocontrol for the agro-environmental sustainability.

中文翻译：

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昆虫病原线虫 (EPNs) 的内共生微生物及其作为农业环境可持续性生物防治剂的应用

由于过度使用杀虫剂等多种因素，地球上的生物多样性日益减少。化学农药的使用影响环境和微生物。应该提高人们对化学农药残留毒性危害的认识，以实现农业环境的可持续性。昆虫病原线虫 (EPN) 是细菌-蠕虫寄生虫，与 Xenorhabdus 和 Photorhabdus 属表现出经典的共生关系。线虫及其内共生细菌具有生物防治潜力，可用于减少化学农药。已经报道了生物制剂的应用并导致病原体的显着减少。此外，这些生物制剂是可生物降解的，环保且易于应用，用于保护作物免受多种病原微生物的侵害。线虫-细菌复合物对多种对作物有害的细菌、真菌、线虫和昆虫有效。除了生物防治潜力外，内共生菌还产生多种次级代谢化合物、外酶和有毒化合物，这些化合物具有抗生素、抗真菌、杀线虫、杀螨和抗癌的特性。本综述涉及来自 EPN 的内共生微生物的多样性及其在农业环境可持续性生物防治中的作用。内共生体产生多种次级代谢化合物、外酶和有毒化合物，具有抗生素、抗真菌、杀线虫、杀螨和抗癌特性。本综述涉及来自 EPN 的内共生微生物的多样性及其在农业环境可持续性生物防治中的作用。内共生体产生多种次级代谢化合物、外酶和有毒化合物，具有抗生素、抗真菌、杀线虫、杀螨和抗癌特性。本综述涉及来自 EPN 的内共生微生物的多样性及其在农业环境可持续性生物防治中的作用。