Adsorbents composed of polyaniline nanostructures or their derivatives immobilized on magnetic nanoparticles had gained increasing interest for application in dispersive micro-solid phase extraction. However, reproducible binding between polymeric PANI nanopaterials and magnetic nanomaterials are still a challenging task. Furthermore, other challenges are the enhancement of physical and chemical stability of adsorbent magnetic nanoparticles as well as improvement of polymeric PANI nanoparticles selectivity towards target analytes. This work described the reproducible preparation of a nanocomposite of aniline-anthranilic acid co-polymeric nanorods with silica coated magnetite nanoparticles by physical mixing of its basic components. The prepared nanocomposite had proven stability against chemical and atmospheric attack. The formed nanocomposite in this work had advantages regarding stability and selectivity towards fluoroquinolones as compared with analogues prepared from polyaniline polymers and/or uncoated magnetite nanoparticles. The selectivity of the formed adsorbent was further optimized for microextraction of four fluoroquinolone antibacterial agents. The application of the prepared nanocomposite was exemplified in microextraction of the studied fluoroquinolones from spiked milk samples to enable their detection down to their stated maximum residue limits.

由固定在磁性纳米颗粒上的聚苯胺纳米结构或其衍生物组成的吸附剂在分散微固相萃取中的应用越来越受到关注。然而，聚合聚苯胺纳米材料和磁性纳米材料之间的可重复结合仍然是一项具有挑战性的任务。此外，其他挑战是提高吸附磁性纳米粒子的物理和化学稳定性以及提高聚合物聚苯胺纳米粒子对目标分析物的选择性。这项工作描述了通过物理混合其基本成分，可重现地制备具有二氧化硅涂层的磁铁矿纳米粒子的苯胺-邻氨基苯甲酸共聚物纳米棒的纳米复合材料。制备的纳米复合材料已证明对化学和大气攻击具有稳定性。与由聚苯胺聚合物和/或未涂覆的磁铁矿纳米颗粒制备的类似物相比，在这项工作中形成的纳米复合材料在稳定性和对氟喹诺酮类药物的选择性方面具有优势。进一步优化了所形成吸附剂的选择性，用于四种氟喹诺酮类抗菌剂的微萃取。制备的纳米复合材料的应用以从加标牛奶样品中微萃取所研究的氟喹诺酮类药物为例，以使其检测到其规定的最大残留限量。进一步优化了所形成吸附剂的选择性，用于四种氟喹诺酮类抗菌剂的微萃取。制备的纳米复合材料的应用以从加标牛奶样品中微萃取所研究的氟喹诺酮类药物为例，以使其检测到其规定的最大残留限量。进一步优化了所形成吸附剂的选择性，用于四种氟喹诺酮类抗菌剂的微萃取。制备的纳米复合材料的应用以从加标牛奶样品中微萃取所研究的氟喹诺酮类药物为例，以使其检测到其规定的最大残留限量。