Assessing estrogen concentrations in biological systems can provide valuable information on physiological processes, which is crucial for the early diagnosis of many diseases. Because estrogens are present in the human body in low concentrations and in a wide dynamic range, analytical methods with high sensitivity and specificity are required for their determination in complex biological matrices.

中文翻译：

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化学衍生辅助液相色谱-电喷雾电离-串联质谱法测定人血清中雌激素

评估生物系统中的雌激素浓度可以提供有关生理过程的宝贵信息，这对于许多疾病的早期诊断至关重要。由于雌激素在人体内以低浓度和宽动态范围存在，因此在复杂的生物基质中测定雌激素需要具有高灵敏度和特异性的分析方法。