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Shining a FLASHlight on Ultrahigh Dose-Rate Radiation and Possible Late Toxicity
Clinical Cancer Research ( IF 10.0 ) Pub Date : 2022-07-06 , DOI: 10.1158/1078-0432.ccr-22-1255
Amit Maity 1, 2, 3 , Constantinos Koumenis 1
Affiliation  

Summary A recent study reported results from a clinical trial in cats and from experiments in mini-pigs in which a single dose of radiotherapy was delivered at ultrahigh dose rates (FLASH). There was acceptable acute toxicity; however, some animals suffered severe late toxicity, raising caution in the design of future trials. See related article by Rohrer Bley et al., p. 3814

中文翻译:

闪光灯照射超高剂量率辐射和可能的后期毒性

摘要 最近的一项研究报告了猫临床试验和小型猪实验的结果,其中以超高剂量率 (FLASH) 进行单剂量放射治疗。有可接受的急性毒性;然而,一些动物遭受了严重的晚期毒性,因此在设计未来的试验时需要谨慎。请参阅 Rohrer Bley 等人的相关文章,第 17 页。3814
更新日期:2022-07-06
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