BACKGROUND AND PURPOSE Little is known about the outcome after receiving total hip arthroplasty (THA), specifically in young patients. We identified different recovery trajectories in young patients using data from the Dutch Arthroplasty Register (LROI). We also explored whether risk factors commonly associated with functional outcome were associated with recovery trajectory. PATIENTS AND METHODS We used HOOS-PS score data up to 1 year postoperatively from the LROI from all patients younger than 55 years who received a primary THA between 2014 and 2019. To investigate whether different recovery trajectories could be distinguished, we performed latent class growth analysis (LCGA). Subsequently, we used multinomial logistic regression analyses to explore factors associated with class membership. RESULTS 3,207 patients were included. LCGA identified 3 groups of patients: optimal responders (75%), good responders (21%), and poor responders (4.7%). Female sex (RR 1.1; 95% CI 1.1-1.1), ASA II (RR 1.1; CI 1.0-1.1), ASA III-IV (RR 1.1; CI 1.0-1.2), smoking (RR 1.1; CI 1.0-1.1), cemented fixation (RR 1.2; CI 1.1-1.2), and a 22-28 mm head diameter (RR 1.1; CI 1.0-1.2) were associated with "good responder" class membership. ASA II (RR 1.1; 1.0-1.2), ASA III-IV (RR 1.2; 1.1-1.3), smoking (RR 1.2; CI 1.1-1.2), and hybrid fixation (RR 1.2; CI 1.0-1.2) were associated with "poor responder" class membership. INTERPRETATION 3 recovery trajectories could be identified. Female sex, higher ASA classifications, smoking, cemented or hybrid fixation, and small head diameter were associated with a suboptimal result after primary THA in young patients. These findings can aid in the process to determine which patients are at risk of a suboptimal outcome.

中文翻译：

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患者报告的初次全髋关节置换术后 95% 的年轻患者的结果有所改善：从荷兰关节置换登记处确定 3,207 名 55 岁以下患者的 3 条恢复轨迹。

背景和目的 关于接受全髋关节置换术 (THA) 后的结果知之甚少，尤其是在年轻患者中。我们使用来自荷兰关节成形术登记处 (LROI) 的数据确定了年轻患者的不同恢复轨迹。我们还探讨了通常与功能结果相关的风险因素是否与恢复轨迹相关。患者和方法 我们使用了 2014 年至 2019 年间接受初次全髋关节置换术的所有 55 岁以下患者的 LROI 术后长达 1 年的 HOOS-PS 评分数据。为了研究是否可以区分不同的恢复轨迹，我们进行了潜在类别增长分析（LCGA）。随后，我们使用多项逻辑回归分析来探索与班级成员相关的因素。结果 包括 3,207 名患者。LCGA 确定了 3 组患者：最佳反应者 (75%)、良好反应者 (21%) 和较差反应者 (4.7%)。女性（RR 1.1；95% CI 1.1-1.1），ASA II（RR 1.1；CI 1.0-1.1），ASA III-IV（RR 1.1；CI 1.0-1.2），吸烟（RR 1.1；CI 1.0-1.1） 、骨水泥固定（RR 1.2；CI 1.1-1.2）和 22-28 mm 头部直径（RR 1.1；CI 1.0-1.2）与“良好反应者”等级成员相关。ASA II（RR 1.1；1.0-1.2）、ASA III-IV（RR 1.2；1.1-1.3）、吸烟（RR 1.2；CI 1.1-1.2）和混合固定（RR 1.2；CI 1.0-1.2）与“反应迟钝”班级成员。解释 可以确定 3 个恢复轨迹。女性、较高的 ASA 分级、吸烟、骨水泥或混合固定以及小头径与年轻患者初次全髋关节置换后的次优结果相关。