The humoral response and antibodies against SARS-CoV-2 infection,Nature Immunology

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The humoral response and antibodies against SARS-CoV-2 infection
Nature Immunology ( IF 27.7 ) Pub Date : 2022-06-27 , DOI: 10.1038/s41590-022-01248-5
Hai Qi _{1,

2,

3,

4,

5,

6} , Bo Liu _{1,

2,

3} , Xinquan Wang _{6,

7} , Linqi Zhang _{3,

4,

6,

8}

Affiliation

Two and a half years into the COVID-19 pandemic, we have gained many insights into the human antibody response to the causative SARS-CoV-2 virus. In this Review, we summarize key observations of humoral immune responses in people with COVID-19, discuss key features of infection- and vaccine-induced neutralizing antibodies, and consider vaccine designs for inducing antibodies that are broadly protective against different variants of the SARS-CoV-2 virus.

中文翻译：

抗 SARS-CoV-2 感染的体液反应和抗体

COVID-19 大流行两年半以来，我们对人类抗体对致病性 SARS-CoV-2 病毒的反应有了很多了解。在这篇综述中，我们总结了对 COVID-19 患者体液免疫反应的主要观察结果，讨论了感染和疫苗诱导的中和抗体的主要特征，并考虑了用于诱导抗体的疫苗设计，这些抗体可广泛预防 SARS 的不同变体- CoV-2 病毒。

更新日期：2022-06-27

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