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A genome and gene catalog of glacier microbiomes
Nature Biotechnology ( IF 33.1 ) Pub Date : 2022-06-27 , DOI: 10.1038/s41587-022-01367-2
Yongqin Liu 1, 2, 3 , Mukan Ji 1 , Tao Yu 3, 4 , Julian Zaugg 5 , Alexandre M Anesio 6 , Zhihao Zhang 2, 3 , Songnian Hu 3, 4 , Philip Hugenholtz 5 , Keshao Liu 2 , Pengfei Liu 1 , Yuying Chen 2, 3 , Yingfeng Luo 3, 4 , Tandong Yao 2
Affiliation  

Glaciers represent a unique inventory of microbial genetic diversity and a record of evolution. The Tibetan Plateau contains the largest area of low-latitude glaciers and is particularly vulnerable to global warming. By sequencing 85 metagenomes and 883 cultured isolates from 21 Tibetan glaciers covering snow, ice and cryoconite habitats, we present a specialized glacier microbial genome and gene catalog to archive glacial genomic and functional diversity. This comprehensive Tibetan Glacier Genome and Gene (TG2G) catalog includes 883 genomes and 2,358 metagenome-assembled genomes, which represent 968 candidate species spanning 30 phyla. The catalog also contains over 25 million non-redundant protein-encoding genes, the utility of which is demonstrated by the exploration of secondary metabolite biosynthetic potentials, virulence factor identification and global glacier metagenome comparison. The TG2G catalog is a valuable resource that enables enhanced understanding of the structure and functions of Tibetan glacial microbiomes.

更新日期:2022-06-27
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