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Recent fall and high imminent risk of fracture in older men and women
Age and Ageing ( IF 6.0 ) Pub Date : 2022-06-27 , DOI: 10.1093/ageing/afac141
Kyoung Min Kim 1, 2 , Li-Yung Lui 1 , Steven R Cummings 1, 3
Affiliation  

Background despite fall history being a well-known risk factor for falls and fractures, the association between very recent falls and imminent fracture risk is not clearly elucidated. Objective to study the very recent (<4 months) fall-related absolute risk of fractures in the following year. Methods two large prospective cohort studies of women (Study of Osteoporotic Fractures [SOF]) and men (Osteoporotic Fractures in Men Study [MrOS]) aged 65 years or older were included. Data on falls were collected every 4 months, and the primary outcomes were any non-spine and hip fractures in the next 12 months. Results a total of 9,704 women contributed 419,149, and 5,994 men contributed 223,885 four-monthly periods of observations during the 14.8-year SOF and 12.6-year MrOS follow-up. Falls within 4 months indicated a high risk of non-spine and hip fractures in the following year for both sexes; in women, a recent fall indicated an 8.1% absolute risk of a non-spine fracture within 1 year, a 2.5-fold higher risk than that in women without falls, a 2.5% absolute risk of hip fracture, and a 3.1-fold increased risk. Falls increased the risk of fractures regardless of whether a fracture occurred or not. Men had similar risk patterns, albeit with a lower absolute risk of fracture. Conclusions in older people, a fall within 4 months indicates a high risk of fracture in the next year, regardless of fracture occurrence. A recent fall warrants urgent evaluation and consideration of treatments to reduce the imminent risk of fractures.

中文翻译:

老年男性和女性最近跌倒和骨折的高风险

背景 尽管跌倒史是跌倒和骨折的众所周知的危险因素,但最近的跌倒与即将发生的骨折风险之间的关联尚未明确阐明。目的研究近期(<4个月)跌倒相关的第二年骨折绝对风险。方法 纳入两项大型前瞻性队列研究,对象为 65 岁或以上的女性(骨质疏松性骨折研究 [SOF])和男性(男性骨质疏松性骨折研究 [MrOS])。每 4 个月收集一次跌倒数据,主要结果是接下来 12 个月内的任何非脊柱和髋部骨折。结果 在 14.8 年的 SOF 和 12.6 年的 MrOS 随访期间,共有 9,704 名女性贡献了 419,149 个观察期,5,994 名男性贡献了 223,885 个四个月观察期。4 个月内跌倒表明男女在接下来的一年中发生非脊柱和髋部骨折的风险很高;在女性中,近期跌倒表明 1 年内发生非脊柱骨折的绝对风险为 8.1%,比未跌倒的女性高 2.5 倍,髋部骨折的绝对风险为 2.5%,增加 3.1 倍风险。无论是否发生骨折,跌倒都会增加骨折的风险。男性有相似的风险模式,尽管骨折的绝对风险较低。结论对于老年人来说,4个月内跌倒表明来年发生骨折的风险很高,无论是否发生骨折。最近的一次跌倒需要紧急评估和考虑治疗方法,以降低即将发生骨折的风险。1年内发生非脊柱骨折的绝对风险为1%,比没有跌倒的女性风险高2.5倍,髋部骨折的绝对风险为2.5%,风险增加3.1倍。无论是否发生骨折,跌倒都会增加骨折的风险。男性有相似的风险模式,尽管骨折的绝对风险较低。结论对于老年人来说,4个月内跌倒表明来年发生骨折的风险很高,无论是否发生骨折。最近的一次跌倒需要紧急评估和考虑治疗方法,以降低即将发生骨折的风险。1年内发生非脊柱骨折的绝对风险为1%,比没有跌倒的女性风险高2.5倍,髋部骨折的绝对风险为2.5%,风险增加3.1倍。无论是否发生骨折,跌倒都会增加骨折的风险。男性有相似的风险模式,尽管骨折的绝对风险较低。结论对于老年人来说,4个月内跌倒表明来年发生骨折的风险很高,无论是否发生骨折。最近的一次跌倒需要紧急评估和考虑治疗方法,以降低即将发生骨折的风险。男性有相似的风险模式,尽管骨折的绝对风险较低。结论对于老年人来说,4个月内跌倒表明来年发生骨折的风险很高,无论是否发生骨折。最近的一次跌倒需要紧急评估和考虑治疗方法,以降低即将发生骨折的风险。男性有相似的风险模式,尽管骨折的绝对风险较低。结论对于老年人来说,4个月内跌倒表明来年发生骨折的风险很高,无论是否发生骨折。最近的一次跌倒需要紧急评估和考虑治疗方法,以降低即将发生骨折的风险。
更新日期:2022-06-27
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