Purpose

Body composition is considered to be associated with obstructive sleep apnea (OSA) severity. This cross-sectional study aimed to examine associations of overnight body composition changes with positional OSA.

Methods

The body composition of patients diagnosed with non-positional and positional OSA was measured before and after overnight polysomnography. Odds ratios (ORs) of outcome variables between the case (positional OSA) and reference (non-positional OSA) groups were examined for associations with sleep-related parameters and with changes in body composition by a logistic regression analysis.

Results

Among 1584 patients with OSA, we used 1056 patients with non-positional OSA as the reference group. We found that a 1-unit increase in overnight changes of total fat percentage and total fat mass were associated with 1.076-fold increased OR (95% confidence interval (CI): 1.014, 1.142) and 1.096-fold increased OR (95% CI: 1.010, 1.189) of positional OSA, respectively (all p < 0.05). Additionally, a 1-unit increase in overnight changes of lower limb fat percentage and upper limb fat mass were associated with 1.043-fold increased OR (95% CI: 1.004, 1.084) and 2.638-fold increased OR (95% CI: 1.313, 5.302) of positional OSA, respectively (all p < 0.05). We observed that a 1-unit increase in overnight changes of trunk fat percentage and trunk fat mass were associated with 1.056-fold increased OR (95% CI: 1.008, 1.106) and 1.150-fold increased OR (95% CI: 1.016, 1.301) of positional OSA, respectively (all p < 0.05).

Conclusion

Our findings indicated that nocturnal changes in the body’s composition, especially total fat mass, total fat percentage, lower limb fat percentage, upper limb fat mass, trunk fat percentage, and trunk fat mass, may be associated with increased odds ratio of positional OSA compared with non-positional OSA.

中文翻译：

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夜间身体成分变化与体位性阻塞性睡眠呼吸暂停的关联

目的

身体成分被认为与阻塞性睡眠呼吸暂停 (OSA) 的严重程度有关。这项横断面研究旨在检查夜间身体成分变化与体位性 OSA 之间的关联。

方法

诊断为非体位性和体位性 OSA 的患者的身体成分在夜间多导睡眠图之前和之后进行了测量。通过逻辑回归分析检查病例（体位性 OSA）和参考（非体位性 OSA）组之间结果变量的比值比 (OR) 与睡眠相关参数和身体成分变化的关联。

结果

在 1584 例 OSA 患者中，我们使用 1056 例非体位性 OSA 患者作为参考组。我们发现总脂肪百分比和总脂肪质量的夜间变化增加 1 个单位与 OR（95% 置信区间 (CI)：1.014、1.142）增加 1.076 倍和 OR（95% CI）增加 1.096 倍相关：位置 OSA 的 1.010、1.189）（所有p  < 0.05）。此外，下肢脂肪百分比和上肢脂肪量的夜间变化增加 1 个单位与 OR 增加 1.043 倍（95% CI：1.004，1.084）和 OR 增加 2.638 倍（95% CI：1.313， 5.302）的位置 OSA，分别（所有p < 0.05)。我们观察到，躯干脂肪百分比和躯干脂肪质量的夜间变化增加 1 个单位与 OR 增加 1.056 倍（95% CI：1.008、1.106）和 OR 增加 1.150 倍（95% CI：1.016、1.301）相关) 的位置 OSA，分别（所有p  < 0.05）。

结论

我们的研究结果表明，与体位性 OSA 相比，身体成分的夜间变化，尤其是总脂肪量、总脂肪百分比、下肢脂肪百分比、上肢脂肪量、躯干脂肪百分比和躯干脂肪量，可能与增加的比值比有关与非体位 OSA。