Lignin is a natural and renewable aromatic raw material of aromatic chemicals and its depolymerization and downstream products conversion has drawn considerable attention. Herein, a series of Ni loaded metal phosphates (Ni/MP, M=Ti, Zr, Nb, La, or Ce) catalysts were fabricated for the hydrodeoxygenation (HDO) of lignin-derived vanillin (VAN) to produce 2-methoxy-4-methylphenol (MMP). It has been demonstrated that 97.25% VAN conversion could be obtained with a yield of 88.39% of MMP under the mild condition of 220 ^oC and 0.5 MPa H₂ for 30 min with 15wt% Ni/ZrP. The highest activity of Ni/ZrP was attributed to its small Ni particle size, large specific surface area, strong metal-support interaction, and optimal acidity. It has been proven that Ni, Lewis acid sites (LAS) and Brønsted acid sites (BAS) have a synergistic effect in VAN conversion: Nano-sized Ni catalyze the dissociation of H₂ to form active hydrogen species (H^•). LAS promote the adsorption and activation of VAN and isopropanol. BAS play a vital role in the dehydration reaction. Additionally, H₂ was the primary hydrogen donor in the system, while isopropanol was the reaction medium as well as the secondary hydrogen donor, helping to reduce the external H₂ supply requirement. By optimizing the reaction conditions and studying the promotion mechanism, we hope to provide an experimental basis for lignin catalytic hydrogenolysis.

木质素是一种天然可再生的芳烃原料，其解聚及下游产品转化备受关注。本文制备了一系列负载镍的金属磷酸盐（Ni/MP、M=Ti、Zr、Nb、La 或 Ce）催化剂，用于木质素衍生的香草醛 (VAN) 的加氢脱氧 (HDO) 以生产 2-甲氧基- 4-甲基苯酚 (MMP)。已经证明，在 220 ^o C 和 0.5 MPa H _{2的温和条件下，VAN 转化率为 97.25%，MMP 收率为 88.39%}用 15wt% Ni/ZrP 处理 30 分钟。Ni/ZrP的最高活性归因于其小Ni粒径、大比表面积、强金属-载体相互作用和最佳酸度。已经证明Ni、Lewis酸位(LAS)和Brønsted酸位(BAS)在VAN转化中具有协同作用：纳米Ni催化H ₂解离形成活性氢物种(H ^• )。LAS促进VAN和异丙醇的吸附和活化。BAS在脱水反应中起着至关重要的作用。此外，H ₂是系统中的主要供氢体，而异丙醇是反应介质和次要供氢体，有助于减少外部 H ₂供应要求。通过优化反应条件和研究促进机理，希望为木质素催化氢解提供实验依据。