We report light-gated channels in a fungus-like protist that are highly selective for K+ over Na+. These microbial rhodopsin channels, named kalium channelrhodopsins, enable robust inhibition of mouse cortical neurons with millisecond precision. In addition, kalium channelrhodopsins reveal a previously unknown potassium selectivity mechanism.

中文翻译：

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长期寻找的光门控钾通道的发现：天然钾通道-视紫红质

我们报告了类真菌原生生物中的光门控通道，其对 K+ 的选择性高于对 Na+ 的选择性。这些称为钾通道视紫红质的微生物视紫红质通道能够以毫秒的精度对小鼠皮层神经元进行强有力的抑制。此外，钾通道视紫红质揭示了一种以前未知的钾选择性机制。