Neuro-immune crosstalk in drug-resistant epilepsy,Nature Neuroscience

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Neuro-immune crosstalk in drug-resistant epilepsy
Nature Neuroscience ( IF 21.2 ) Pub Date : 2022-06-23 , DOI: 10.1038/s41593-022-01112-7
Brian M Andersen _{1,

2} , Francisco J Quintana _{1,

3}

Affiliation

Epilepsy is the most common childhood neurological disease, and nearly 20% of affected children develop drug-resistant childhood epilepsy (DRCE). Using single-cell analysis methods, Kumar et al. have identified pro-inflammatory interactions between microglia and T cells in brain tissue from individuals with DRCE. This work may help to identify therapeutic targets for DRCE.

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