This study, nanoscale α-, β-, γ-cyclodextrin (CD)-metal-organic frameworks (MOFs) were successfully prepared using solvothermal assisted ultrasound method. CD-MOFs were used as nanocarriers to encapsulate catechin (CA), and their encapsulation capacities were evaluated. Encapsulation capacities of CD-MOFs to incorporate CA followed the order: β-CD-MOFs > γ-CD-MOFs > α-CD-MOFs. CA/CD-MOFs were characterized using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) and differential scanning calorimetry (DSC). DSC and SEM results provided evidence for the formation of CA/CD-MOFs. XRD results indicated the new solid crystalline phases formed in CA/CD-MOFs complex. Results of FT-IR showed that CA was combined with CD-MOFs through hydrogen bonding and van der Waals forces. Current research demonstrated that encapsulation of CA within CD-MOFs provided it against light, oxygen and temperature. Moreover, encapsulation by CD-MOFs improved storage stability and bioavailability of CA. Thus, these CA/CD-MOFs have potential to be used as nutritional supplements and functional foods.

本研究采用溶剂热辅助超声方法成功制备了纳米级α-、β-、γ-环糊精（CD）-金属有机骨架（MOFs）。CD-MOFs 被用作纳米载体来封装儿茶素 (CA)，并评估了它们的封装能力。CD-MOFs 结合 CA 的封装能力遵循以下顺序：β-CD-MOFs > γ-CD-MOFs > α-CD-MOFs。使用扫描电子显微镜 (SEM)、傅里叶变换红外光谱 (FT-IR)、X 射线衍射 (XRD) 和差示扫描量热法 (DSC) 对 CA/CD-MOF 进行了表征。DSC 和 SEM 结果为 CA/CD-MOF 的形成提供了证据。XRD 结果表明在 CA/CD-MOFs 复合物中形成了新的固晶相。FT-IR结果表明CA通过氢键和范德华力与CD-MOFs结合。目前的研究表明，在 CD-MOF 中封装 CA 使其能够抵抗光、氧气和温度。此外，CD-MOFs 的封装提高了 CA 的储存稳定性和生物利用度。因此，这些 CA/CD-MOFs 具有用作营养补充剂和功能性食品的潜力。