Cyclohexanone oxime (CHO), a key C=N organic compound in the manufacture of nylon 6, is conventionally synthesized via a multistep process that consumes expensive NH₃ and H₂ under harsh conditions. Herein, we report the direct electro-synthesis of CHO from low-cost NO, H₂O, and cyclohexanone over a carbon catalyst under ambient conditions. A high Faradaic efficiency of 44.8% and a formation rate of 10.7 mg cm⁻² h⁻¹ for CHO were achieved at −0.4 V versus the reversible hydrogen electrode through optimizing the surface hydrophobicity of the catalyst to facilitate diffusion of reactants. Controlled experiments and ¹⁵N-labeling tests verified that the nitrogen in the CHO product originates from NO. Density functional theory calculations showed that the armchair edge of carbon could be the active site with a reaction mechanism following NO → NO∗ → HNO∗ → HNOH∗ → NH₂OH → CHO. This work suggests a direct, green, and low-cost synthesis strategy for high-value CHO from pollutant NO.

环己酮肟 (CHO) 是尼龙 6 制造中的关键 C=N 有机化合物，通常通过多步工艺合成，该工艺在恶劣条件下消耗昂贵的 NH ₃和 H _{2 。}在此，我们报告了在环境条件下在碳催化剂上由低成本的 NO、H ₂ O 和环己酮直接电合成 CHO。通过优化催化剂的表面疏水性以促进反应物的扩散，与可逆氢电极相比，在-0.4 V 时，CHO 的法拉第效率为 44.8%，形成速率为 10.7 mg cm ^-2 h ^{-1 。}对照实验和¹⁵N标记测试证实CHO产物中的氮来源于NO。密度泛函理论计算表明，碳的扶手椅边缘可能是活性位点，其反应机理为NO→NO*→HNO*→HNOH*→NH ₂ OH→CHO。这项工作提出了一种直接、绿色和低成本的从污染物 NO 合成高价值 CHO 的策略。