Despite the fact that ectodermal dysplasia (ED) is a rare disease, it is often seen in a tertiary clinic. ED affects ectodermal tissues such as skin, hair, teeth, nails, and sweat glands. Patients usually have sparse light hair, deformed nails, and dry skin. They suffer from dental abnormalities such as oligodontia (absence of 6 or more teeth) or complete anodontia; salivation can also be affected. The absence of teeth can be the overriding problem for both patients and their parents, and lead to substantial social ostracisation. This study aims to summarise the facts about the disease, especially dental treatment options based on data drawn from a representative Czech cohort.

中文翻译：

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外胚层发育不良：复杂牙科护理在其跨学科管理中的重要作用。

尽管外胚层发育不良 (ED) 是一种罕见疾病，但它经常出现在三级诊所。ED 影响外胚层组织，例如皮肤、头发、牙齿、指甲和汗腺。患者通常有稀疏的浅色头发、变形的指甲和皮肤干燥。他们患有牙齿异常，例如少牙（缺少 6 颗或更多牙齿）或完全无牙；唾液分泌也会受到影响。对于患者和他们的父母来说，没有牙齿可能是最重要的问题，并导致严重的社会排斥。本研究旨在总结有关该疾病的事实，尤其是基于捷克代表性队列数据的牙科治疗方案。