Herein, a molecularly imprinted surface-enhanced Raman spectroscopy (SERS) sensor was developed for the selective capture and sensitive detection of tryptamine in foods. The SERS sensor exploited silver nanoparticle-decorated TiO₂ (TiO₂@Ag) substrates for Raman signal enhancement via synergistic effect of electromagnetic enhancement and photoinduced charge-transfer, whilst surface functionalization with the molecularly imprinted polymer ensured selective tryptamine capture. The SERS spectrum of tryptamine on the sensor closely matched that predicted by density functional simulations. The SERS intensity for tryptamine on the developed TiO₂@Ag@MIP sensor increased linearly with the logarithm of the tryptamine concentration over the range of 10^-6-10^-2 mol L^-1, with a LOD of 4.85×10^-7 mol L^-1. Tryptamine was detected in a spiked white vinegar sample, and its recoveries were in the range of 92.00%-111.40%. The SERS sensor could be used for the detection of tryptamine in actual samples.

在此，开发了一种分子印迹表面增强拉曼光谱 (SERS) 传感器，用于选择性捕获和灵敏检测食品中的色胺。SERS 传感器利用银纳米颗粒装饰的 TiO ₂ (TiO ₂ @Ag) 基板通过电磁增强和光诱导电荷转移的协同效应增强拉曼信号，同时分子印迹聚合物的表面功能化确保选择性捕获色胺。传感器上色胺的 SERS 光谱与密度泛函模拟预测的光谱非常匹配。_{开发的 TiO 2} @Ag@MIP 传感器上色胺的 SERS 强度在10 ^-6范围内随色胺浓度的对数线性增加-10 ^-2 mol L ^-1，检测限为 4.85×10 ^-7 mol L ^-1。在加标的白醋样品中检测到色胺，其回收率在 92.00%-111.40% 范围内。SERS传感器可用于检测实际样品中的色胺。