A novel sol-gel pyridylethylthiopropyl functionalized silica-based sorbent was synthesized and utilized in an on-line column preconcentration system coupled with flame atomic absorption spectrometry for metal determination. The developed platform was used for the determination of Pb(II) and Cu(II) in beer samples, since there are limited automatic methods for routine analysis of alcoholic beverage.

For a preconcentration time of 60 s, the calculated enhancement factors were 96 for Cu(II) and 130 for Pb(II). The limits of detection were 0.33 μg L^-1 and 1.98 μg L^-1 for Cu(II) and Pb(II), respectively. Moreover, the RSDs were less than 2.9% indicating good method precision. The method was successfully employed for the analysis of commercially available beers. The Cu(II) content of the samples was 1.6-21.8 μg L^-1 and the Pb(II) content was 7.3-17.6 μg L^-1. The developed manifold exhibited operational simplicity and good performance characteristics, indicating its potential utilization for routine analysis in beer industry.

合成了一种新型溶胶-凝胶吡啶基乙基硫丙基官能化二氧化硅基吸附剂，并将其用于在线色谱柱预浓缩系统与火焰原子吸收光谱法相结合的金属测定。由于酒精饮料常规分析的自动方法有限，因此开发的平台用于测定啤酒样品中的 Pb(II) 和 Cu(II)。

对于 60 秒的预浓缩时间，计算得出的增强因子对于 Cu(II) 为 96，对于 Pb(II) 为 130。Cu(II) 和 Pb(II)的检测限分别为 0.33 μg L ^-1和 1.98 μg L ^-1。此外，RSD 小于 2.9%，表明方法精度良好。该方法成功地用于分析市售啤酒。样品中Cu(II)含量为1.6-21.8 μg L ^-1，Pb(II)含量为7.3-17.6 μg L ^-1。开发的歧管表现出操作简单和良好的性能特征，表明其在啤酒行业常规分析中的潜在用途。