Alzheimer's disease genetic burden is associated with mid-life depression among persons with normal cognition,Alzheimer's & Dementia

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Alzheimer's disease genetic burden is associated with mid-life depression among persons with normal cognition
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2022-06-21 , DOI: 10.1002/alz.12716
Thomas S Wingo _{1,

2,

3} , Ekaterina S Gerasimov ₂ , Se Min Canon ₂ , James J Lah _{1,

2} , Allan I Levey _{1,

2} , Aliza P Wingo _{4,

5}

Affiliation

Despite an established link between depression and higher Alzheimer's disease (AD) risk, it is unclear whether the conditions share pathophysiology. Here, we investigated whether depression manifesting after age 50 is associated with a genetic predisposition to AD.

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