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Pro-Con Debate: Do We Need Quantitative Neuromuscular Monitoring in the Era of Sugammadex?
Anesthesia & Analgesia ( IF 4.6 ) Pub Date : 2022-07-01 , DOI: 10.1213/ane.0000000000005925
Manfred Blobner 1, 2 , Markus W Hollmann 3 , Markus M Luedi 4 , Ken B Johnson 5
Affiliation  

In this Pro-Con article, we debate the merits of using quantitative neuromuscular blockade monitoring. Consensus guidelines recommend their use to guide the administration of nondepolarizing neuromuscular blockade and reversal agents. A major impediment to this guideline is that until recently, reliable quantitative neuromuscular blockade monitors have not been widely available. Without them, anesthesia providers have been trained with and are adept at using a variety of qualitative neuromuscular blockade monitors otherwise known as peripheral nerve stimulators. Although perhaps less accurate, anesthesia providers find them reliable and easy to use. They have a long track record of using them with the perception that their use leads to effective neuromuscular blockade reversal and minimizes clinically significant adverse events from residual neuromuscular blockade. In the recent past, 2 disruptive developments have called upon anesthesia care providers to reconsider their practice in neuromuscular blockade administration, reversal, and monitoring. These include: (1) commercialization of more reliable quantitative neuromuscular monitors and (2) widespread use of sugammadex, a versatile reversal agent of neuromuscular blockade. Sugammadex appears to be so effective at rapidly and effectively reversing even the deepest of neuromuscular blockades, and it has left anesthesia providers wondering whether quantitative monitoring is indeed necessary or whether conventional, familiar, and less expensive qualitative monitoring will suffice? This Pro-Con debate will contrast anesthesia provider perceptions with evidence surrounding the use of quantitative neuromuscular blockade monitors to explore whether quantitative neuromuscular monitoring (NMM) is just another technology solution looking for a problem or a significant advance in NMM that will improve patient safety and outcomes.



中文翻译:

正反辩论:在舒更葡糖时代,我们是否需要定量神经肌肉监测?

在这篇 Pro-Con 文章中,我们讨论了使用定量神经肌肉阻滞监测的优点。共识指南推荐使用它们来指导非去极化神经肌肉阻滞剂和逆转剂的给药。该指南的一个主要障碍是,直到最近,可靠的定量神经肌肉阻滞监测仪还没有广泛使用。没有它们,麻醉提供者已经接受过培训,并且擅长使用各种定性神经肌肉阻滞监测器,也称为周围神经刺激器。尽管可能不太准确,但麻醉提供者发现它们可靠且易于使用。他们有长期使用它们的记录,认为它们的使用会导致有效的神经肌肉阻滞逆转,并最大限度地减少残留神经肌肉阻滞引起的临床显着不良事件。在最近的过去,2 项颠覆性的发展要求麻醉护理提供者重新考虑他们在神经肌肉阻滞剂给药、逆转和监测方面的实践。其中包括:(1)更可靠的定量神经肌肉监测器的商业化和(2)广泛使用舒更葡糖,一种多用途的神经肌肉阻滞剂。Sugammadex 似乎在快速有效地逆转最深的神经肌肉阻滞方面非常有效,它让麻醉提供者想知道是否确实需要定量监测,或者是否常规、熟悉、更便宜的定性监测就足够了吗?这场赞成与反对的辩论会将麻醉提供者的看法与围绕使用定量神经肌肉阻滞监测仪的证据进行对比,以探索定量神经肌肉监测 (NMM) 是否只是另一种技术解决方案,寻找问题或 NMM 的重大进步,以提高患者的安全性和结果。

更新日期:2022-07-01
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