Epidermis can grow its surface by activating mitotic division in basal stem cells. In a recent issue of Nature, Chan et al. (2022) show that under high demand for new skin, differentiated epidermal cells in zebrafish divide without DNA synthesis, forming cells in the new surface with reduced and abnormal genomes.

中文翻译：

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为了皮肤屏障的完整性，角质形成细胞在细胞周期上偷工减料

表皮可以通过激活基底干细胞的有丝分裂来生长其表面。在最近一期《自然》杂志上， Chan 等人。(2022) 表明，在对新皮肤的高需求下，斑马鱼中分化的表皮细胞在没有 DNA 合成的情况下分裂，在新表面形成基因组减少和异常的细胞。