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Detoxification mechanism of vinegar-processed Kansui revealed by systematic phytochemical analysis using ultrahigh-performance liquid chromatography diode array detection tandem mass spectrometry, ultrahigh-performance liquid chromatography high-resolution mass spectrometry and in silico drug target identification
Rapid Communications in Mass Spectrometry ( IF 1.8 ) Pub Date : 2022-06-18 , DOI: 10.1002/rcm.9332 Lian Liu 1 , Jiangchun Li 2 , Jizhong Lv 3 , Haipeng Jiang 1 , Fen-Er Chen 1, 4
Rapid Communications in Mass Spectrometry ( IF 1.8 ) Pub Date : 2022-06-18 , DOI: 10.1002/rcm.9332 Lian Liu 1 , Jiangchun Li 2 , Jizhong Lv 3 , Haipeng Jiang 1 , Fen-Er Chen 1, 4
Affiliation
The dried roots of Euphorbia kansui L., known as Kansui, are used to treat ascites and edema in traditional Chinese medicine. However, the toxicity of this herb has seriously restricted its clinical application. A unique vinegar-processing method has been used to reduce its toxicity since the time of ancient China. However, the detoxification mechanism underlying such vinegar processing has not been fully revealed. To find the answer, the process-induced changes in components should be carefully investigated.
更新日期:2022-06-18