Multiple microbial exopolysaccharides have been reported in recent decade with their structural and functional features. Gellan gum (GG) is among these emerging biopolymers with versatile properties. Low production yield, high downstream cost, and abundant market demand have made GG a high cost material. Hence, an understanding on the various possibilities to develop cost-effective gellan gum bioprocess is desirable. This review focuses on details of upstream and downstream process of GG from an industrial perspective. It emphasizes on GG producing Sphingomonas spp., updates on biosynthesis, strain and media engineering, kinetic modeling, bioreactor design and scale-up considerations. Details of the downstream operations with possible modifications to make it cost-effective and environmentally sustainable have been discussed. The updated regulatory criteria for GG as a food ingredient and analytical tools required to validate the same have been briefly discussed. Derivatives of GG and their applications in various industrial segments have also been highlighted.

近十年来，已经报道了多种微生物胞外多糖及其结构和功能特征。结冷胶 (GG) 是这些具有多种特性的新兴生物聚合物之一。产量低、下游成本高、市场需求旺盛，使GG成为高成本材料。因此，需要了解开发具有成本效益的结冷胶生物工艺的各种可能性。本综述从工业角度重点介绍了 GG 上游和下游工艺的细节。它强调GG产生鞘氨醇单胞菌spp.，有关生物合成、应变和介质工程、动力学建模、生物反应器设计和放大考虑的更新。已经讨论了可能进行修改以使其具有成本效益和环境可持续性的下游操作的细节。简要讨论了 GG 作为食品成分的更新监管标准和验证其所需的分析工具。GG的衍生物及其在各个工业领域的应用也得到了强调。