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Advances in fermentative production, purification, characterization and applications of gellan gum
Bioresource Technology ( IF 9.7 ) Pub Date : 2022-06-17 , DOI: 10.1016/j.biortech.2022.127498
Manoj J Dev 1 , Rahul G Warke 2 , Gangadhar M Warke 2 , Girish B Mahajan 2 , Tanuja A Patil 2 , Rekha S Singhal 1
Affiliation  

Multiple microbial exopolysaccharides have been reported in recent decade with their structural and functional features. Gellan gum (GG) is among these emerging biopolymers with versatile properties. Low production yield, high downstream cost, and abundant market demand have made GG a high cost material. Hence, an understanding on the various possibilities to develop cost-effective gellan gum bioprocess is desirable. This review focuses on details of upstream and downstream process of GG from an industrial perspective. It emphasizes on GG producing spp., updates on biosynthesis, strain and media engineering, kinetic modeling, bioreactor design and scale-up considerations. Details of the downstream operations with possible modifications to make it cost-effective and environmentally sustainable have been discussed. The updated regulatory criteria for GG as a food ingredient and analytical tools required to validate the same have been briefly discussed. Derivatives of GG and their applications in various industrial segments have also been highlighted.

中文翻译:


结冷胶发酵生产、纯化、表征及应用进展



近十年来报道了多种微生物胞外多糖及其结构和功能特征。结冷胶 (GG) 是具有多种特性的新兴生物聚合物之一。生产良率低、下游成本高、市场需求充沛,使得GG成为高成本材料。因此,需要了解开发具有成本效益的结冷胶生物工艺的各种可能性。本篇综述主要从产业角度对GG上下游流程进行详细介绍。它强调 GG 生产物种、生物合成、菌株和介质工程、动力学建模、生物反应器设计和放大注意事项的更新。讨论了下游运营的细节以及可能的修改,以使其具有成本效益和环境可持续性。简要讨论了 GG 作为食品成分的最新监管标准以及验证其所需的分析工具。 GG的衍生物及其在各个工业领域的应用也得到了重点介绍。
更新日期:2022-06-17
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