The advent of enhanced radiological imaging techniques has facilitated the diagnosis of cystic liver lesions. Concomitantly, the evidence base supporting the management of these diseases has matured over the last decades. As a result, comprehensive clinical guidance on the subject matter is warranted. These Clinical Practice Guidelines cover the diagnosis and management of hepatic cysts, mucinous cystic neoplasms of the liver, biliary hamartomas, polycystic liver disease, Caroli disease, Caroli syndrome, biliary hamartomas and peribiliary cysts. On the basis of in-depth review of the relevant literature we provide recommendations to navigate clinical dilemmas followed by supporting text. The recommendations are graded according to the Oxford Centre for Evidence-Based Medicine system and categorised as ‘weak’ or ‘strong’. We aim to provide the best available evidence to aid the clinical decision-making process in the management of patients with cystic liver disease.

增强放射成像技术的出现促进了囊性肝病变的诊断。与此同时，支持这些疾病管理的证据基础在过去几十年中已经成熟。因此，有必要针对该主题提供全面的临床指导。这些临床实践指南涵盖了肝囊肿、肝脏粘液性囊性肿瘤、胆道错构瘤、多囊肝病、Caroli病、Caroli综合征、胆道错构瘤和胆管周围囊肿的诊断和治疗。在深入回顾相关文献的基础上，我们提供了解决临床困境的建议，并附有支持文本。这些建议根据牛津循证医学中心系统进行分级，分为“弱”或“强”。我们的目标是提供最佳的现有证据，以帮助囊性肝病患者治疗的临床决策过程。