Description of a European memory clinic cohort undergoing amyloid-PET: The AMYPAD Diagnostic and Patient Management Study,Alzheimer's & Dementia

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Description of a European memory clinic cohort undergoing amyloid-PET: The AMYPAD Diagnostic and Patient Management Study
Alzheimer's & Dementia ( IF 14.0 ) Pub Date : 2022-06-17 , DOI: 10.1002/alz.12696
Daniele Altomare _{1,

2} , Lyduine Collij ₃ , Camilla Caprioglio _{1,

2} , Philip Scheltens ₄ , Bart N M van Berckel ₃ , Isadora Lopes Alves ₃ , Johannes Berkhof ₅ , Yvonne de Gier ₃ , Valentina Garibotto _{6,

7} , Christian Moro _{1,

2} , Léa Poitrine _{1,

2} , Julien Delrieu _{8,

9} , Pierre Payoux _{10,

11} , Laure Saint-Aubert _{10,

12} , José Luis Molinuevo _{13,

14} , Oriol Grau-Rivera _{13,

15,

16} , Juan-Domingo Gispert _{13,

15,

17} , Carolina Minguillón _{13,

15,

16} , Karine Fauria _{13,

16} , Marta Felez Sanchez ₁₃ , Andreea Rădoi ₁₃ , Alexander Drzezga _{18,

19,

20} , Frank Jessen ₂₁ , Claus Escher ₂₁ , Philip Zeyen ₂₁ , Agneta Nordberg _{22,

23} , Irina Savitcheva ₂₄ , Vesna Jelic ₂₅ , Zuzana Walker _{26,

27} , Ho-Yun Lee ₂₇ , Lean Lee ₂₆ , Jean-François Demonet ₂₈ , Sonia Plaza Wuthrich ₂₈ , Rossella Gismondi ₂₉ , Gill Farrar ₃₀ , Frederik Barkhof _{3,

31} , Andrew W Stephens ₂₉ , Giovanni B Frisoni _{1,

2} ,

Affiliation

Laboratory of Neuroimaging of Aging (LANVIE), University of Geneva, Geneva, Switzerland.
Geneva Memory Center, Geneva University Hospitals, Geneva, Switzerland.
Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centers (UMC) - Location VUmc, Amsterdam, The Netherlands.
Alzheimer Center, Department of Neurology, Amsterdam University Medical Centers (UMC) - Location VUmc, Amsterdam, The Netherlands.
Department of Epidemiology and Data Science, Amsterdam University Medical Centers (UMC) - Location VUmc, Amsterdam, The Netherlands.
Laboratory of Neuroimaging and Innovative Molecular Tracers (NIMTlab), Geneva University Neurocenter and Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospitals, Geneva, Switzerland.
Gérontopôle, Department of Geriatrics, Toulouse University Hospital, Toulouse, France.
Maintain Aging Research team, CERPOP, Inserm, Université Paul Sabatier, Toulouse, France.
Department of Nuclear Medicine, Toulouse University Hospital, Toulouse, France.
Toulouse NeuroImaging Center (ToNIC), Inserm, Université Paul Sabatier, Toulouse, France.
Toulouse NeuroImaging Center (ToNIC), Université de Toulouse, Inserm, Université Paul Sabatier, Toulouse, France.
Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.
H. Lundbeck A/S, Copenhagen, Denmark.
Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.
Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain.
Centro de Investigación Biomédica en Red Bioingeniería, Biomateriales y Nanomedicina, (CIBER-BBN), Barcelona, Spain.
Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany.
German Center for Neurodegenerative Diseases (DZNE), Bonn-Cologne, Germany.
Institute of Neuroscience and Medicine (INM-2), Molecular Organization of the Brain, Forschungszentrum Jülich, Germany.
Department of Psychiatry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Department of Neurobiology, Care Sciences and Society, Center of Alzheimer Research, Karolinska Institutet, Stockholm, Sweden.
Theme Aging, Karolinska University Hospital, Stockholm, Sweden.
Medical Radiation Physics and Nuclear Medicine, Section for Nuclear Medicine, Karolinska University Hospital, Stockholm, Sweden.
Cognitive Disorders Clinic, Theme Inflammation and Aging, Karolinska University Hospital-Huddinge, Stockholm, Sweden.
Division of Psychiatry, University College London, London, UK.
St. Margaret's Hospital, Essex Partnership University NHS Foundation Trust, Essex, UK.
Leenaards Memory Center, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Life Molecular Imaging, Berlin, Germany.
GE Healthcare, Amersham, UK.
Institutes of Neurology and Healthcare Engineering, UCL, London, UK.

AMYPAD Diagnostic and Patient Management Study (DPMS) aims to investigate the clinical utility and cost-effectiveness of amyloid-PET in Europe. Here we present participants’ baseline features and discuss the representativeness of the cohort.

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