Mapping the preclinical dementia phase is important for early detection and evaluation of interventions. We assessed the trajectories of cognitive decline in preclinical dementia over 12 years and investigated whether being a fast decliner across 6 years is associated with increased risk of dementia the following 6 years.

中文翻译：

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认知能力下降和痴呆发展的轨迹：一项为期 12 年的纵向研究


绘制临床前痴呆阶段对于早期发现和评估干预措施非常重要。我们评估了 12 年来临床前痴呆症认知能力下降的轨迹，并调查了 6 年内认知能力快速下降是否与接下来 6 年内痴呆风险增加相关。