Current trends, applications, and challenges of coatings on additive manufacturing based biopolymers: A state of art review,Polymer Composites

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Current trends, applications, and challenges of coatings on additive manufacturing based biopolymers: A state of art review
Polymer Composites ( IF 4.8 ) Pub Date : 2022-06-16 , DOI: 10.1002/pc.26809
Shrutika Sharma ₁ , Vishal Gupta ₁ , Deepa Mudgal ₁

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Healing of bone fractures highly depends on the biocompatibility, stability in biological conditions, biodegradability, technical functionality, and shelf-life of biomaterials. Metallic biomaterials offer excellent mechanical properties and biocompatibility. However, metallic bone implants result in stress shielding, release of toxic ions, excessive wear, and corrosion. Polymer materials are being explored for bone implants due to their light-weight, biocompatibility, biodegradability, and absence of stress shielding. In the new era, additive manufacturing (AM) is being preferred due to its capability of fabricating customer specific implants with minimum material wastage. However, AM based polymer implants lack in mechanical strength and biological properties. Surface modification of polymeric substrates using coatings and incorporation of bioadditives have been regarded as alternatives for improvement of mechanical and biological properties. This review discusses about various coating techniques and gives an overview about coatings and bioadditives that can be used for enhancement of properties. From the review, it is evident that reinforcement of hydroxyapatite to polylactic acid resulted in prevention of crack growth during shape recovery cycles which can be used for self-fitting implants. Coatings have been successful in enhancing hydrophilicity, mechanical properties, anti-biofouling, antibacterial and anti-coagulative properties, adhesion, proliferation, and differentiation of cells on the coated surface. This review also discusses the challenges that need to be overcome for progression in this field.

中文翻译：

基于增材制造的生物聚合物涂层的当前趋势、应用和挑战：最新技术评论

骨折的愈合高度依赖于生物材料的生物相容性、生物条件稳定性、生物降解性、技术功能和保质期。金属生物材料具有优异的机械性能和生物相容性。然而，金属骨植入物会导致应力屏蔽、有毒离子的释放、过度磨损和腐蚀。由于聚合物材料重量轻、生物相容性、可生物降解性和无应力屏蔽，正在探索用于骨植入物的聚合物材料。在新时代，增材制造 (AM) 因其能够以最少的材料浪费制造客户特定的植入物而受到青睐。然而，基于增材制造的聚合物植入物缺乏机械强度和生物学特性。使用涂层和掺入生物添加剂对聚合物基材进行表面改性已被视为改善机械和生物性能的替代方法。本综述讨论了各种涂层技术，并概述了可用于增强性能的涂层和生物添加剂。从评论中可以看出，羟基磷灰石对聚乳酸的增强作用可以防止形状恢复周期中的裂纹生长，这可用于自装配植入物。涂层已成功地增强涂层表面上细胞的亲水性、机械性能、抗生物污染、抗菌和抗凝血性能、粘附、增殖和分化。

更新日期：2022-06-16

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