In Nature, Chou et al. identify a subset of innate-like αβ T cells with high cytotoxic potential that accumulate in tumors and elicit an anti-tumor response. Given their capacity to maintain an activation state without undergoing exhaustion, these innate-like T cells may represent effective therapeutic agents for cell-based approaches.

中文翻译：

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先天性 T 细胞：抗癌免疫的一个有前景的资产

在《自然》杂志上，Chou 等人。鉴定出具有高细胞毒性潜力的先天性 αβ T 细胞子集，它们在肿瘤中积累并引发抗肿瘤反应。鉴于它们能够维持激活状态而不经历耗竭，这些先天样 T 细胞可能代表基于细胞的方法的有效治疗剂。