Owing to the presence of significant levels of toxic furan compounds reported globally in commercial foods by various food authorities, the objectives of this study were to develop an analytical method for determination of furan and its 10 derivatives in commercial foods using headspace-solid phase microextraction (HS-SPME)-Arrow coupled with gas chromatography–tandem mass spectrometry. Furan and its 10 derivatives were separated within 10 min by employing an HP-5MS capillary column with d₄-furan as the internal standard for quantitation. The most optimal sample weight and extraction time for various commercial food samples, respectively, ranged from 1 to 5 g and 10–15 min depending on the sample variety. For extraction, carboxen/poly(dimethylsiloxane) (CAR/PDMS) cellulose was used with the temperature at 30 °C, equilibration time of 15 min, and desorption time of 3 min. The limit of detection ranged from 0.001 to 1.071 ng/g, while the limit of quantitation ranged from 0.003 to 3.571 ng/g. A high precision and accuracy were obtained for this method. The total furan content in commercial foods ranged from nd to 40 725.85 ng/g, in which the mean contents were the highest for brewed coffee (35 082.26 ng/g) and canned coffee (25 152.22 ng/g), while the lowest were for potato chip and cookies (0.57–1.48 ng/g), donut (1.50 ng/g), milk (0.34–30.38 ng/g), and oat (6.56 ng/g).

中文翻译：

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HS-SPME Arrow结合气相色谱-串联质谱法测定商品食品中呋喃及其衍生物的改进分析方法

由于各食品当局在全球范围内报告的商业食品中存在大量有毒呋喃化合物，本研究的目的是开发一种使用顶空固相微萃取测定商业食品中呋喃及其 10 种衍生物的分析方法。 HS-SPME)-箭头与气相色谱-串联质谱联用。使用d ₄的 HP-5MS 毛细管柱可在 10 分钟内分离呋喃及其 10 种衍生物-呋喃作为定量的内标。各种商业食品样品的最佳样品重量和提取时间分别为 1 至 5 克和 10 至 15 分钟，具体取决于样品种类。对于萃取，使用羧基/聚（二甲基硅氧烷）（CAR/PDMS）纤维素，温度为 30 °C，平衡时间为 15 分钟，解吸时间为 3 分钟。检测限为 0.001 至 1.071 ng/g，定量限为 0.003 至 3.571 ng/g。该方法获得了较高的精密度和准确度。商品食品中呋喃总含量在 nd~40 725.85 ng/g 之间，其中冲煮咖啡（35 082.26 ng/g）和罐装咖啡（25 152.22 ng/g）的平均含量最高，而最低的是用于薯片和饼干 (0.57–1.48 ng/g)、甜甜圈 (1.50 ng/g)、牛奶 (0.