With gradual warming or increased frequency and magnitude of high temperature, heat stress adversely affects plant growth and eventually reduces plant productivity and quality. Plants have evolved complex mechanisms to sense and respond to heat stress which are crucial to avoiding cell damage and maintaining cellular homeostasis. Recently, 33″,55″-cyclic adenosine monophosphate (cAMP) has been proved to be an important signaling molecule participating in plant adaptation to heat stress by affecting multi-level regulatory networks. Significant progress has been made on many fronts of cAMP research, particularly in understanding the downstream signaling events that culminate in the activation of stress-responsive genes, mRNA translation initiation, vesicle trafficking, the ubiquitin-proteasome system, autophagy, HSPs-assisted protein processing, and cellular ion homeostasis to prevent heat-related damage and to preserve cellular and metabolic functions. In this present review, we summarize recent works on the genetic and molecular mechanisms of cAMP in plant response to heat stress which could be useful in finding thermotolerant key genes to develop heat stress-resistant varieties and that have the potential for utilizing cAMP as a chemical regulator to improve plant thermotolerance. New directions for future studies on cAMP are discussed.

中文翻译：

---

cAMP 是一种有前途的植物适应热应激的调节分子

随着逐渐变暖或高温频率和幅度的增加，热应激会对植物生长产生不利影响，并最终降低植物的生产力和质量。植物已经进化出复杂的机制来感知和响应热应激，这对于避免细胞损伤和维持细胞稳态至关重要。最近，33″,55″-环磷酸腺苷（cAMP）被证明是通过影响多层次调控网络参与植物适应热胁迫的重要信号分子。在 cAMP 研究的许多方面都取得了重大进展，特别是在了解导致应激反应基因激活、mRNA 翻译起始、囊泡运输、泛素-蛋白酶体系统、自噬、HSP 辅助蛋白质加工的下游信号事件方面, 和细胞离子稳态，以防止与热有关的损伤并保持细胞和代谢功能。在本综述中，我们总结了最近关于 cAMP 在植物对热胁迫反应中的遗传和分子机制的研究，这些研究可能有助于寻找耐热关键基因以开发耐热胁迫品种，并有可能将 cAMP 作为一种化学物质。调节器以提高植物的耐热性。讨论了 cAMP 未来研究的新方向。我们总结了最近关于 cAMP 在植物对热胁迫反应中的遗传和分子机制的研究，这可能有助于寻找耐热关键基因以开发耐热胁迫品种，并有可能利用 cAMP 作为化学调节剂来提高植物耐热性. 讨论了 cAMP 未来研究的新方向。我们总结了最近关于 cAMP 在植物对热胁迫反应中的遗传和分子机制的研究，这可能有助于寻找耐热关键基因以开发耐热胁迫品种，并有可能利用 cAMP 作为化学调节剂来提高植物耐热性. 讨论了 cAMP 未来研究的新方向。