The totality of evidence from large-scale, randomized, controlled clinical trials and mechanistic studies in the laboratory has provided six crucial lessons about the emerging role of SGLT2 inhibitors to prevent the onset of heart failure in patients at high risk and slow the progression of heart failure in patients with established disease.

中文翻译：

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心力衰竭患者使用 SGLT2 抑制剂的六个教训

来自大规模、随机、对照临床试验和实验室机制研究的全部证据提供了关于 SGLT2 抑制剂在预防高危患者心力衰竭发作和减缓心脏进展方面的新兴作用的六个重要教训已确诊疾病的患者失败。