Methylation is a frequent modification of glycans and polysaccharides. This process relies on the transport of cytosolic S-adenosyl-l-methionine (SAM) into the Golgi lumen. This work identifies Golgi-localized major facilitator superfamily transporter members as putative SAM transporters in plants and reveals their importance for polysaccharide methylation and maintenance of the properties of cell walls.

中文翻译：

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关闭多糖甲基化的大门


甲基化是聚糖和多糖的常见修饰。该过程依赖于胞浆 S-腺苷-L-甲硫氨酸 (SAM) 转运至高尔基体腔。这项工作将高尔基体定位的主要促进子超家族转运蛋白成员鉴定为植物中假定的 SAM 转运蛋白，并揭示了它们对多糖甲基化和维持细胞壁特性的重要性。