A new study describes a microscope combining three-photon excitation and adaptive optics capable of high-resolution in vivo imaging of fine neuronal structures in the mouse cortex through the intact skull. The authors demonstrate the use of this platform to guide precise laser-mediated microsurgery and for accurate and sensitive functional calcium imaging.

中文翻译：

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以高分辨率对大脑网络和功能进行非侵入性成像

一项新研究描述了一种结合了三光子激发和自适应光学的显微镜，能够通过完整的头骨对小鼠皮层中的精细神经元结构进行高分辨率体内成像。作者演示了使用该平台来指导精确的激光介导的显微外科手术以及准确灵敏的功能性钙成像。