Present study exhibited the oxidative potential of microwave radiation (MWR) leading to the neurodegeneration in rats. Wistar rats were exposed at 2100 MHz frequency for 4 h/day, 5 days/week/3 months. Animals were exposed at an estimated specific absorption rate (0.453 W/kg) and power density (8.237 µW/m²). After exposure irradiated group was compared with control group. Results indicated that microwave exposure significantly increased the levels of serological triglycerides and cholesterol. Oxidative stress is observed through alteration of glutathione homeostasis followed by activated inflammatory response further confirmed by pro and anti-inflammatory cytokines in the exposed group. Histopathological assessments and electron microscopic observation confirmed a significant change in the myelination pattern and cellular organelles in the brain of exposed animals. Taking everything into account it can be concluded that chronic exposure of 2100-MHz frequency caused oxidative stress, which leads to neural damage and demyelination and may affect neural communication.

本研究展示了微波辐射 (MWR) 的氧化电位导致大鼠神经退行性变。Wistar大鼠在 2100 MHz 频率下暴露 4 小时/天、5 天/周/3 个月。动物以估计的特定吸收率 (0.453 W/kg) 和功率密度 (8.237 µW/m ²）。照射后照射组与对照组进行比较。结果表明，微波暴露显着增加了血清甘油三酯和胆固醇的水平。通过改变谷胱甘肽稳态观察到氧化应激，随后激活的炎症反应进一步被暴露组中的促炎和抗炎细胞因子证实。组织病理学评估和电子显微镜观察证实了暴露动物大脑中髓鞘形成模式和细胞器的显着变化。综合考虑可以得出结论，长期暴露于 2100 MHz 频率会导致氧化应激，从而导致神经损伤和脱髓鞘，并可能影响神经交流。