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Three residues in the BTB domain promote a good partnership between NuRD and Thpok
Science Immunology ( IF 17.6 ) Pub Date : 2022-06-10 , DOI: 10.1126/sciimmunol.abq1408
Kazuki Okuyama 1 , Ichiro Taniuchi 1
Affiliation  

Among the BTB-ZF transcription factor family, three amino acids in the BTB domain make Thpok unique in repressing cytotoxic lineage-related genes via recruitment of the NuRD chormatin-remodeling complex (see the related Research Article by Gao et al. ).

中文翻译:

BTB 结构域中的三个残基促进了 NuRD 和 Thpok 之间的良好伙伴关系

在 BTB-ZF 转录因子家族中,BTB 结构域中的三个氨基酸使 Thpok 在通过募集 NuRD 染色质重塑复合物抑制细胞毒性谱系相关基因方面具有独特性(参见 Gao 的相关研究文章等。)。
更新日期:2022-06-10
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