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Intravenous chlorpromazine for acute paediatric migraine.
Emergency Medicine Australasia ( IF 1.7 ) Pub Date : 2022-06-09 , DOI: 10.1111/1742-6723.13985
Ruth Mc Löllgen 1, 2, 3, 4 , Franz E Babl 1, 2, 5 , Mark T Mackay 2, 5, 6 , Ashley Hill 1, 2 , Greta M Palmer 2, 5, 7
Affiliation  

OBJECTIVE In paediatric migraine, ibuprofen, acetaminophen and triptans are safe, effective therapies but there is scant paediatric data informing second-line emergency treatment. METHODS Retrospective cohort study of children diagnosed with migraine at a tertiary children's hospital ED. RESULTS There were 207 children with migraine over a 1 year period. 46% received simple oral analgesia. 25% intravenous chlorpromazine, of whom 45% received further analgesia. CONCLUSIONS While intravenous chlorpromazine as second-line agent was mostly safe, it had unclear efficacy given the requirement for further treatment and hospital admissions.

中文翻译:

静脉注射氯丙嗪治疗急性小儿偏头痛。

目的 在小儿偏头痛中,布洛芬、对乙酰氨基酚和曲坦类药物是安全、有效的治疗方法,但缺乏可用于二线紧急治疗的儿科数据。方法 对在一所三级儿童医院 ED 诊断为偏头痛的儿童进行回顾性队列研究。结果 1 年期间有 207 名儿童患有偏头痛。46% 接受简单的口服镇痛药。25% 静脉注射氯丙嗪,其中 45% 接受进一步镇痛。结论虽然静脉氯丙嗪作为二线药物大多是安全的,但考虑到进一步治疗和住院的需要,其疗效尚不明确。
更新日期:2022-06-09
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