OBJECTIVE In paediatric migraine, ibuprofen, acetaminophen and triptans are safe, effective therapies but there is scant paediatric data informing second-line emergency treatment. METHODS Retrospective cohort study of children diagnosed with migraine at a tertiary children's hospital ED. RESULTS There were 207 children with migraine over a 1 year period. 46% received simple oral analgesia. 25% intravenous chlorpromazine, of whom 45% received further analgesia. CONCLUSIONS While intravenous chlorpromazine as second-line agent was mostly safe, it had unclear efficacy given the requirement for further treatment and hospital admissions.

中文翻译：

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静脉注射氯丙嗪治疗急性小儿偏头痛。

目的 在小儿偏头痛中，布洛芬、对乙酰氨基酚和曲坦类药物是安全、有效的治疗方法，但缺乏可用于二线紧急治疗的儿科数据。方法 对在一所三级儿童医院 ED 诊断为偏头痛的儿童进行回顾性队列研究。结果 1 年期间有 207 名儿童患有偏头痛。46% 接受简单的口服镇痛药。25% 静脉注射氯丙嗪，其中 45% 接受进一步镇痛。结论虽然静脉氯丙嗪作为二线药物大多是安全的，但考虑到进一步治疗和住院的需要，其疗效尚不明确。