Objective To compare outcomes from arthroscopic partial meniscectomy versus physical therapy in young patients with traumatic meniscal tears. Methods We conducted a multicentre, open-labelled, randomised controlled trial in patients aged 18–45 years, with a recent onset, traumatic, MRI-verified, isolated meniscal tear without knee osteoarthritis. Patients were randomised to arthroscopic partial meniscectomy or standardised physical therapy with an optional delayed arthroscopic partial meniscectomy after 3-month follow-up. The primary outcome was the International Knee Documentation Committee (IKDC) score (best 100, worst 0) at 24 months, which measures patients’ perception of symptoms, knee function and ability to participate in sports activities. Results Between 2014 and 2018, 100 patients were included (mean age 35.1 (SD 8.1), 76% male, 34 competitive or elite athletes). Forty-nine were randomised to arthroscopic partial meniscectomy and 51 to physical therapy. In the physical therapy group, 21 patients (41%) received delayed arthroscopic partial meniscectomy during the follow-up period. In both groups, improvement in IKDC scores was clinically relevant during follow-up compared with baseline scores. At 24 months mean (95% CI) IKDC scores were 78 (71 to 84) out of 100 points in the arthroscopic partial meniscectomy group and 78 (71 to 84) in the physical therapy group with a between group difference of 0.1 (95% CI −7.6 to 7.7) points out of 100. Conclusions In this trial involving young patients with isolated traumatic meniscal tears, early arthroscopic partial meniscectomy was not superior to a strategy of physical therapy with optional delayed arthroscopic partial meniscectomy at 24-month follow-up. Trial registration . Data are available on reasonable request. Individual de-identified participant data that underlie the results reported in this paper (text, tables, figures and appendices) and the study protocol will be shared if requested. Data will be available beginning 12 months and ending 5 years following publication of this paper. Data will be available for researchers who provide a methodologically sound scientific proposal, which has been approved by an ethical committee. Proof of the latter should be provided. Analyses should achieve the aims as reported in the approved proposal. Proposals for data should be directed to m.reijman@erasmusmc.nl.

中文翻译：

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年轻研究人群中关节镜部分半月板切除术与物理疗法治疗创伤性半月板撕裂：一项随机对照试验


目的 比较年轻外伤性半月​​板撕裂患者的关节镜部分半月板切除术与物理治疗的结果。方法 我们对 18-45 岁的患者进行了一项多中心、开放标签、随机对照试验，这些患者近期发病、外伤、经 MRI 验证、孤立性半月板撕裂，无膝骨关节炎。 3 个月随访后，患者被随机接受关节镜部分半月板切除术或标准化物理治疗，并可选择延迟关节镜部分半月板切除术。主要结果是 24 个月时国际膝关节文献委员会 (IKDC) 评分（最佳 100，最差 0），该评分衡量患者对症状的感知、膝关节功能和参与体育活动的能力。结果 2014 年至 2018 年间，纳入了 100 名患者（平均年龄 35.1 岁 (SD 8.1)，76% 为男性，34 名竞技或精英运动员）。 49 名患者随机接受关节镜部分半月板切除术，51 名患者接受物理治疗。在物理治疗组中，21 名患者（41%）在随访期间接受了延迟关节镜部分半月板切除术。在随访期间，与基线评分相比，两组 IKDC 评分的改善具有临床相关性。 24 个月时，关节镜部分半月板切除术组的平均 IKDC 评分 (95% CI) 为 78 分 (71 至 84)（满分 100 分），物理治疗组为 78 分 (71 至 84)，组间差异为 0.1 (95%) CI -7.6 至 7.7）分（满分 100 分）。结论 在这项涉及孤立性外伤性半月​​板撕裂的年轻患者的试验中，在 24 个月的随访中，早期关节镜部分半月板切除术并不优于物理治疗策略和可选的延迟关节镜部分半月板切除术。试用注册。可根据合理要求提供数据。 如果需要，将共享本文报告的结果（文本、表格、图形和附录）和研究方案的个人去识别化参与者数据。数据将于本文发表后 12 个月至 5 年内提供。数据将提供给提供方法上合理的科学提案并已得到伦理委员会批准的研究人员。应提供后者的证明。分析应实现已批准提案中报告的目标。数据提案应发送至 m.reijman@erasmusmc.nl。