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In Alzheimer's disease, amyloid beta accumulation is a protective mechanism that ultimately fails
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2022-06-08 , DOI: 10.1002/alz.12701
Elise Brøchner Rischel 1 , Michael Gejl 2 , Birgitte Brock 3 , Jørgen Rungby 4 , Albert Gjedde 1, 5
Affiliation  

Here, we claim that amyloid beta (Aβ) accumulation is a protective mechanism that ultimately fails. We predict that more Aβ accumulates in regions with higher rates of glucose metabolism, reaching a maximum followed by progression of pathology.

中文翻译:


在阿尔茨海默病中,β淀粉样蛋白积累是一种最终失效的保护机制



在这里,我们声称β淀粉样蛋白(Aβ)积累是一种最终失败的保护机制。我们预测,更多的 Aβ 会在葡萄糖代谢率较高的区域积聚,并达到最大值,随后出现病理进展。
更新日期:2022-06-08
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