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Extremophilic lipases for industrial applications: A general review
Biotechnology Advances ( IF 12.1 ) Pub Date : 2022-06-07 , DOI: 10.1016/j.biotechadv.2022.108002
K Vivek 1 , G S Sandhia 1 , S Subramaniyan 1
Affiliation  

With industrialization and development in modern science enzymes and their applications increased widely. There is always a hunt for new proficient enzymes with novel properties to meet specific needs of various industrial sectors. Along with the high efficiency, the green and eco-friendly side of enzymes attracts human attention, as they form a true answer to counter the hazardous and toxic conventional industrial catalyst. Lipases have always earned industrial attention due to the broad range of hydrolytic and synthetic reactions they catalyse. When these catalytic properties get accompanied by features like temperature stability, pH stability, and solvent stability lipases becomes an appropriate tool for use in many industrial processes. Extremophilic lipases offer the same, thermostable: hot and cold active thermophilic and psychrophilic lipases, acid and alkali resistant and active acidophilic and alkaliphilic lipases, and salt tolerant halophilic lipases form excellent biocatalyst for detergent formulations, biofuel synthesis, ester synthesis, food processing, pharmaceuticals, leather, and paper industry. An interesting application of these lipases is in the bioremediation of lipid waste in harsh environments. The review gives a brief account on various extremophilic lipases with emphasis on thermophilic, psychrophilic, halophilic, alkaliphilic, and acidophilic lipases, their sources, biochemical properties, and potential applications in recent decades.



中文翻译:

工业应用的极端嗜酸性脂肪酶:综述

随着现代科学酶的产业化和发展,酶及其应用广泛增加。一直在寻找具有新特性的新型精通酶,以满足各个工业部门的特定需求。除了高效之外,酶的绿色和环保方面也引起了人们的关注,因为它们形成了对抗有害和有毒的传统工业催化剂的真正答案。脂肪酶因其催化的广泛的水解和合成反应而一直受到工业界的关注。当这些催化特性伴随着温度稳定性、pH 稳定性和溶剂稳定性等特性时,脂肪酶就成为许多工业过程中使用的合适工具。Extremophilic 脂肪酶提供相同的热稳定性:热和冷活性嗜热和嗜冷脂肪酶、耐酸碱和活性嗜酸和嗜碱脂肪酶以及耐盐嗜盐脂肪酶形成了用于洗涤剂配方、生物燃料合成、酯合成、食品加工、制药、皮革和造纸工业的优良生物催化剂。这些脂肪酶的一个有趣应用是在恶劣环境中对脂质废物进行生物修复。该综述简要介绍了各种嗜热脂肪酶,重点介绍了嗜热、嗜冷、嗜盐、嗜碱和嗜酸脂肪酶,它们的来源、生化特性和近几十年来的潜在应用。生物燃料合成、酯合成、食品加工、制药、皮革和造纸工业。这些脂肪酶的一个有趣应用是在恶劣环境中对脂质废物进行生物修复。该综述简要介绍了各种嗜热脂肪酶,重点介绍了嗜热、嗜冷、嗜盐、嗜碱和嗜酸脂肪酶,它们的来源、生化特性和近几十年来的潜在应用。生物燃料合成、酯合成、食品加工、制药、皮革和造纸工业。这些脂肪酶的一个有趣应用是在恶劣环境中对脂质废物进行生物修复。该综述简要介绍了各种嗜热脂肪酶,重点介绍了嗜热、嗜冷、嗜盐、嗜碱和嗜酸脂肪酶,它们的来源、生化特性和近几十年来的潜在应用。

更新日期:2022-06-07
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