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Assessment of CAR-T Cell-Mediated Cytotoxicity in 3D Microfluidic Cancer Co-Culture Models for Combination Therapy
IEEE Open Journal of Engineering in Medicine and Biology ( IF 2.7 ) Pub Date : 5-27-2022 , DOI: 10.1109/ojemb.2022.3178302
Karla Paterson 1, 2 , Sarah Paterson 2 , Theresa Mulholland 2 , Seth B Coffelt 3, 4 , Michele Zagnoni 1, 2
Affiliation  

Microfluidic platforms and protocols can provide powerful, cost-effective and miniaturised in vitro assays to preclinically assess CAR-T cell therapies in solid tumours.

中文翻译:


联合治疗的 3D 微流控癌症共培养模型中 CAR-T 细胞介导的细胞毒性评估



微流控平台和方案可以提供强大、经济高效且小型化的体外测定,以评估实体瘤中的 CAR-T 细胞疗法的临床前。
更新日期:2024-08-28
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