This study is aimed at comparing the dosimetric differences of restricting beamlets passing in protecting ovaries between helical tomotherapy (HT) and volumetric-modulated arc therapy (VMAT) for patients with cervical cancer, and particularly comparing the γ passing rates of ovaries between the two techniques by independent dose calculations. 15 patients with cervical cancer who had undergone ovarian transposition were randomly enrolled. The HT and VMAT plans were created for each involved patient. Target quality, organs at risk (OARs) sparing, and γ passing rates of ovaries were compared between HT and VMAT. HT achieved better than VMAT in D, D, D, conformal index and homogeneity index (P < 0.05). Almost all OARs in HT had lower radiation dose than those in VMAT (P < 0.05). All the γ passing rates of the ovaries were 100% for the 15 patients both in HT and VMAT. The results suggests that HT outperforms VMAT in terms of target coverage and OARs sparing. Although the calculated dose to the ovaries was accurate both in HT and VMAT, HT showed further advantages for cervical cancer patients with ovarian protection requirements.

中文翻译：

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螺旋断层放疗与容积调制弧治疗宫颈癌完全阻断卵巢保护的剂量学比较

本研究旨在比较宫颈癌患者螺旋断层放射治疗（HT）和体积调制弧形治疗（VMAT）在保护卵巢方面限制子束通过的剂量差异，特别是比较两种技术的卵巢γ通过率通过独立的剂量计算。随机入组15例接受卵巢移位术的宫颈癌患者。为每位相关患者制定了 HT 和 VMAT 计划。比较 HT 和 VMAT 的目标质量、危及器官 (OAR) 保留和卵巢 γ 通过率。 HT在D、D、D、适形指数和均匀性指数方面均优于VMAT（P < 0.05）。 HT 中几乎所有 OAR 的辐射剂量均低于 VMAT 中的辐射剂量（P < 0.05）。 15例HT和VMAT患者卵巢γ射线通过率均为100%。结果表明，HT 在目标覆盖率和 OAR 保留方面优于 VMAT。尽管在 HT 和 VMAT 中计算出的卵巢剂量都是准确的，但 HT 对于有卵巢保护需求的宫颈癌患者显示出进一步的优势。