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Mini-Review on Bioanalytical Estimation of Brinzolamide
Current Pharmaceutical Analysis ( IF 0.7 ) Pub Date : 2022-03-01 , DOI: 10.2174/1573412917666210812103414
Ajay B. Madrewar 1 , Ashwini S. Deshpande 1 , Sankha Bhattacharya 1
Affiliation  

Abstract:Brinzolamide is a treatment option for glaucoma. As glaucoma is the third leadingcause of blindness, there is a need for analytical methods to obtain an effective drug with greatprecision and accuracy. Even if brinzolamide is official in IP and USP, different analytical methodsstill need to be brought in one place, which would help attain better results and easy comparisonfor other analysis specifications and procedures. This review helps to understand and gatherdifferent analysis techniques or biological fluid techniques of brinzolamide in a dosage form.These techniques include UV spectroscopy, HPLC, LC-MS, and TLC densitometry.

中文翻译:

布林佐胺生物分析评价小评

摘要:布林佐胺是青光眼的一种治疗选择。由于青光眼是导致失明的第三大原因,因此需要分析方法来获得具有极高精确度和准确性的有效药物。即使布林佐胺在 IP 和 USP 中是官方的,但仍然需要将不同的分析方法集中到一个地方,这将有助于获得更好的结果并便于与其他分析规范和程序进行比较。这篇综述有助于理解和收集剂型中布林佐胺的不同分析技术或生物流体技术。这些技术包括紫外光谱、HPLC、LC-MS 和 TLC 光密度测定。
更新日期:2022-03-01
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